Table 2 Global Logitudinal and Circumferential Strain and Strain-Rate.

From: Range Variability in CMR Feature Tracking Multilayer Strain across Different Stages of Heart Failure

 

Controls

HFpEF

HFmrEF

HFrEF

#P Value

Controls vs HFpEF

#P Value

Controls vs HFmrEF

#P Value

HFpEF vs HFmrEF

#P Value

HFmrEF vs HFrEF

Global Longitudinal Strain

Endo- (%)

−23.0 ± 3.5

−20.0 ± 3.3

−16.4 ± 2.2

−11.0 ± 3.2

0.020

<0.001

<0.001

<0.001

Myo- (%)

−20.7 ± 2.4

−17.5.0 ± 2.6

−14.5 ± 2.1

−9.6 ± 2.7

0.001

<0.001

<0.001

<0.001

Epi- (%)

−15.7 ± 1.9

−12.2 ± 2.1

−10.6 ± 2.3

−7.7 ± 2.3

<0.001

<0.001

0.044

<0.001

†P Value Repeated Measure ANOVA in Pathology Groups

<0.001

<0.001

<0.001

<0.001

    

Global Circumferential Strain

Endo- (%)

−34.5 ± 6.2

−33.9 ± 5.7

−20.0 ± 4.2

−12.3 ± 4.2

0.51

<0.001

<0.001

<0.001

Myo- (%)

−21.9 ± 3.8

−21.3 ± 2.2

−13.0 ± 3.4

−8.0 ± 2.7

0.39

<0.001

<0.001

<0.001

Epi- (%)

−11.4 ± 2.0

−10.9 ± 2.3

−7.9 ± 2.3

−4.5 ± 1.9

0.54

<0.001

<0.001

<<0.001

Global Longitudinal

Strain Rate

Endo- (%/s)

−1.18 ± 0.19

−1.13 ± 0.30

−0.85 ± 0.16

−0.58 ± 0.13

0.52

<0.001

<0.001

<0.001

Myo- (%/s)

−1.05 ± 0.14

−0.94 ± 0.20

−0.75 ± 0.13

−0.50 ± 0.11

0.089

<0.001

<0.001

<0.001

Epi- (%/s)

−0.84 ± 0.11

−0.71 ± 0.15

−0.60 ± 0.10

−0.46 ± 0.17

0.008

<0.001

0.010

<0.001

†P Value Repeated Measure ANOVA in Pathology Groups

<0.001

<0.001

<0.001

<0.001

    

Global Circumferential

Strain Rate

Endo- (%/s)

−1.79 ± 0.41

−1.86 ± 0.54

−1.02 ± 0.27

−0.72 ± 0.20

0.68

<0.001

<0.001

<0.001

Myo- (%/s)

−1.14 ± 0.20

−1.12 ± 0.19

−0.70 ± 0.16

−0.53 ± 0.16

0.76

<0.001

<0.001

0.002

Epi- (%/s)

−0.70 ± 0.13

−0.69 ± 0.08

−0.51 ± 0.13

−0.40 ± 0.17

0.74

<0.001

<0.001

0.005

†P Value Repeated Measure ANOVA in Pathology Groups

<0.001

<0.001

<0.001

<0.001

    
  1. Endo- sub-endocardial myocardium layer, Myo- mid-myocardial layer, Epi- sub-epicardial myocardium layer, Controls – normal control volunteers, HFpEF – heart failure with preserved ejection fraction, HFmrEF – heart failure with mid-range ejection fraction, HFrEF – heart failure with reduced ejection fraction. Comparison between pathology groups are assessed through an ANOVA 1-way. #P values characterize multiple mean comparisons between groups, adjusted with the Bonferroni method, †P values characterize repeated measures ANOVA for intrasubject comparisons. A P value level above 0.05 is considered significant.
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