Table 3 Regional Longitudinal and Circumferential Strain.

From: Range Variability in CMR Feature Tracking Multilayer Strain across Different Stages of Heart Failure

 

Controls

HFpEF

HFmrEF

HFrEF

P Value

Controls vs HFpEF

P Value

Controls vs HFmrEF

P Value

HFpEF vs HFmrEF

P Value

HFmrEF vs HFrEF

Regional Longitudinal Strain - Basal Segments

Endo- (%)

−24.7 ± 3.3

−20.5 ± 2.9

−18.4 ± 3.7

−14.3 ± 2.9

<0.001

<0.001

0.06

0.005

Myo- (%)

−24.7 ± 3.5

−22.1 ± 2.6

−18.9 ± 3.5

−14.3 ± 3.1

0.029

<0.001

0.005

<0.001

Epi- (%)

−23.4 ± 3.6

−21.8 ± 3.2

−18.1 ± 4.1

−14.4 ± 3.5

0.15

<0.001

0.01

0.004

Regional Longitudinal Strain - Mid Ventricle Segments

Endo- (%)

−28.0 ± 4.0

−24.7 ± 2.4

−19.6 ± 3.6

−15.8 ± 3.1

0.006

<0.001

<0.001

0.001

Myo- (%)

−27.7 ± 3.8

−24.3 ± 2.8

−20.2 ± 4.0

−15.8 ± 3.5

0.008

<0.001

<0.001

<0.001

Epi- (%)

−26.6 ± 4.3

−22.8 ± 4.0

−19.9 ± 4.1

−15.7 ± 3.8

0.019

<0.001

0.024

0.003

Regional Longitudinal Strain - Apical Segments

Endo- (%)

−25.0 ± 7.3

−23.3 ± 5.7

−19.5 ± 4.9

−13.3 ± 6.1

0.81

0.031

0.016

0.002

Myo- (%)

−19.3 ± 5.1

−16.7 ± 3.6

−14.6 ± 4.6

−10.5 ± 4.3

0.17

0.009

0.18

0.006

Epi- (%)

−14.1 ± 4.2

−11.2 ± 3.0

−10.5 ± 6.5

−8.4 ± 3.2

0.018

0.064

0.82

0.014

Regional Circumferential Strain - Basal Segments

Endo- (%)

−35.3 ± 6.0

−35.3 ± 5.6

−22.1 ± 4.2

−14.7 ± 3.6

0.85

<0.001

<0.001

<0.001

Myo- (%)

−23.6 ± 3.7

−23.0 ± 3.8

−15.9 ± 2.7

−10.1 ± 2.2

0.54

<0.001

<0.001

<0.001

Epi- (%)

−15.6 ± 2.3

−14.2 ± 2.3

−12.1 ± 2.0

−9.2 ± 1.5

0.16

<0.001

0.006

<0.001

Regional Circumferential Strain - Mid Ventricle Segments

Endo- (%)

−32.6 ± 6.0

−32.9 ± 6.8

−21.3 ± 4.8

−14.4 ± 4.1

0.88

<0.001

<0.001

<0.001

Myo- (%)

−21.3 ± 3.9

−21.3 ± 3.2

−14.6 ± 2.7

−10.4 ± 3.3

0.73

<0.001

<0.001

<0.001

Epi- (%)

−14.1 ± 2.2

−14.6 ± 3.9

−10.6 ± 2.1

−8.4 ± 2.7

0.73

<0.001

<0.001

0.003

Regional Circumferential Strain - Apical Segments

Endo- (%)

−38.7 ± 8.3

−35.5 ± 9.1

−24.6 ± 7.7

−16.4 ± 7.3

0.32

<0.001

<0.001

0.001

Myo- (%)

−24.8 ± 4.4

−23.6 ± 4.4

−17.2 ± 4.9

−11.0 ± 5.1

0.44

<0.001

<0.001

<0.001

Epi- (%)

−14.6 ± 3.2

−16.1 ± 4.6

−12.6 ± 4.2

−8.3 ± 4.0

0.24

0.052

0.015

<0.001

  1. Endo- sub-endocardial myocardium layer, Myo- mid-myocardial layer, Epi- sub-epicardial myocardium layer, Controls – normal control volunteers, HFpEF – heart failure with preserved ejection fraction, HFmrEF – heart failure with mid-range ejection fraction, HFrEF – heart failure with reduced ejection fraction. Comparison between pathology groups are assessed through an ANOVA 1-way. A P value level above 0.05 is considered significant.
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