Table 1 Genes that are significantly differently transcribed in JE2ΔclpX relative to JE2 expressing ClpXI265E (1.5 fold cut-off).
Gene* | Predicted Function* | Fold change JE2ΔclpX/JE2XI265E | Padj |
|---|---|---|---|
SAUSA300_0807 | SaPI gene, function unknown | 5,0 | 4,6E-10 |
SAUSA300_0806 | SaPI gene, function unknown | 5,0 | 2,5E-09 |
SAUSA300_0805 | SaPI excisionase | 4,6 | 2,3E-05 |
SAUSA300_0808 | SaPI gene, function unknown | 4,5 | 5,8E-11 |
SAUSA300_0809 | SaPI5 DNA primase | 4,4 | 4,6E-10 |
SAUSA300_0811 | SaPI gene, function unknown | 4,0 | 1,8E-05 |
SAUSA300_0810 | SaPI gene, function unknown | 4,0 | 2,8E-11 |
SAUSA300_0804 | putative transcriptional regulator | 3,9 | 1,6E-10 |
SAUSA300_0813 | SaPI gene, function unknown | 3,6 | 1,7E-10 |
SAUSA300_0812 | SaPI5 phage interference | 3,6 | 1,1E-09 |
SAUSA300_0365 | hypothetical protein SAS009 63aa | 2,6 | 3,2E-04 |
SceD | SceD, WalkR controlled peptidoglycan hydrolases | 2,0 | 5,7E-06 |
SAUSA300_1903 | hypothetical protein, LexA operon | 1,9 | 2,1E-03 |
cwrA | cwrA gene responding to cell wall damage | 1,9 | 6,3E-03 |
divIB | cell division protein | 0,7 | 3,6E-08 |
ureC | urease subunit alpha | 0,7 | 9,2E-03 |
brnQ | branched-chain amino acid transport system II carrier protein | 0,7 | 6,5E-03 |
SAUSA300_2523 | hypothetical protein | 0,7 | 8,5E-03 |
ureB | urease subunit beta | 0,7 | 4,5E-03 |
asp23 | alkaline shock protein 23 | 0,7 | 3,3E-03 |
SAUSA300_2455 | putative fructose-1,6-bisphosphatase | 0,7 | 1,1E-03 |
ureE | urease accessory protein UreE | 0,7 | 6,5E-03 |
opuCd | glycine betaine/carnitine/choline transport system permease | 0,7 | 6,0E-04 |
ureD | urease accessory protein UreD | 0,7 | 5,5E-03 |
murD | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase | 0,6 | 1,6E-23 |
accC | acetyl-CoA carboxylase, biotin carboxylase | 0,6 | 1,8E-03 |
dapD | tetrahydrodipicolinate acetyltransferase | 0,6 | 1,7E-03 |
SAUSA300_1565 | putative urea amidolyase | 0,6 | 4,3E-03 |
SAUSA300_2524 | hypothetical protein | 0,6 | 9,4E-03 |
ptsG | phosphotransferase system, glucose-specific IIABC component | 0,6 | 7,2E-03 |
rpmH | 50 S ribosomal protein L34 | 0,6 | 5,7E-03 |
SAUSA300_0437 | NLPA lipoprotein | 0,6 | 3,0E-04 |
SAUSA300_2589 | SasA adjesom cell wall anchor domain-containing protein | 0,6 | 5,7E-09 |
thrC | threonine synthase | 0,6 | 3,3E-04 |
thrB | homoserine kinase | 0,6 | 2,1E-05 |
yfiA | ribosomal subunit interface protein | 0,6 | 3,7E-03 |
SAUSA300_2548 | hypothetical protein | 0,6 | 4,8E-05 |
hom | homoserine dehydrogenase, hom | 0,6 | 9,4E-04 |
SAUSA300_1739 | hypothetical protein | 0,6 | 8,0E-05 |
SAUSA300_1740 | hypothetical protein, lipid anchored | 0,6 | 1,1E-04 |
cap1C | capsular polysaccharide biosynthesis protein Cap1C | 0,6 | 1,9E-03 |
clfA | clumping factor A | 0,6 | 1,4E-03 |
glpT | glycerol-3-phosphate transporter | 0,6 | 5,3E-04 |
ureA | urease subunit gamma | 0,6 | 5,9E-03 |
esxE | Esx E toxin-antitoxin system (type VII secretion locus) | 0,6 | 4,6E-03 |
SAUSA300_0271 | ABC transporter ATP-binding protein | 0,6 | 5,2E-03 |
SAUSA300_2289 | hypothetical protein | 0,6 | 4,5E-04 |
copZ | copper chaperone copZ | 0,6 | 7,3E-05 |
esxC | EsxC toxin (type VII secretion locus) | 0,6 | 6,2E-03 |
SAUSA300_0273 | hypothetical protein | 0,6 | 6,7E-08 |
nrdD | anaerobic ribonucleoside triphosphate reductase | 0,6 | 4,7E-03 |
SAUSA300_0272 | hypothetical protein | 0,6 | 2,1E-03 |
lip | triacylglycerol lipase | 0,6 | 5,7E-03 |
cap1B | capsular polysaccharide biosynthesis protein Cap1B | 0,6 | 1,4E-05 |
SAUSA300_2538 | amino acid permease family protein | 0,6 | 8,3E-03 |
dapA | dihydrodipicolinate synthase | 0,6 | 3,2E-04 |
spxA | transcriptional regulator Spx | 0,6 | 4,9E-04 |
asd | aspartate semialdehyde dehydrogenase | 0,6 | 2,0E-03 |
SAUSA300_0277 | peptidoglycan hydrolase linked to the type VII secretion locus | 0,6 | 1,8E-04 |
nrdG | anaerobic ribonucleotide reductase, small subunit | 0,6 | 1,2E-03 |
SAUSA300_0558 | putative proline/betaine transporter | 0,6 | 1,6E-04 |
opp-3a | oligopeptide ABC transporter substrate-binding protein | 0,6 | 5,1E-03 |
pbpA | penicillin-binding protein 1 | 0,5 | 8,5E-37 |
SAUSA300_0769 | hypothetical protein | 0,5 | 6,7E-03 |
SAUSA300_1286 | aspartate kinase | 0,5 | 7,9E-04 |
esxB | EsxB toxin (type VII secretion locus) | 0,5 | 2,8E-03 |
SAUSA300_2614 | hypothetical protein | 0,5 | 5,2E-09 |
SAUSA300_2237 | putative urea transporter | 0,5 | 1,4E-03 |
esxD | EsxD toxin (type VII secretion locus) | 0,5 | 2,8E-03 |
SAUSA300_0274 | hypothetical protein | 0,5 | 9,9E-05 |
essC | EssC protein (membrane- bound, type VII secretion) | 0,5 | 5,4E-04 |
SAUSA300_2447 | hypothetical protein | 0,5 | 7,9E-04 |
SAUSA300_0767 | hypothetical protein | 0,5 | 4,6E-03 |
essB | EssB protein (membrane- bound, type VII secretion) | 0,5 | 5,2E-05 |
sarZ | SarZ transcriptional regulator | 0,5 | 3,6E-08 |
SAUSA300_0768 | hypothetical protein | 0,5 | 8,5E-04 |
essA | EssA (membrane- bound, type VII secretion) | 0,5 | 8,4E-04 |
ftsL | cell division protein | 0,5 | 1,2E-15 |
clpX | ATP-binding subunit ClpX | 0,5 | 3,5E-46 |
cudT | BCCT family choline/carnitine/betaine transporter | 0,4 | 1,4E-04 |
esaA | EsaA membrane- bound, type VII secretion | 0,4 | 6,1E-06 |
mraZ | cell division protein MraZ | 0,4 | 1,0E-33 |
mraW | S-adenosyl-methyltransferase MraW | 0,4 | 2,4E-24 |
esxA | EsxA toxin (type VII secretion locus) | 0,4 | 1,8E-05 |
betB | glycine betaine aldehyde dehydrogenase | 0,3 | 8,5E-03 |
