Table 1 Baseline demographic and clinical characteristics of patients with IgG4-RD.
From: Different clinical patterns of IgG4-RD patients with and without eosinophilia
Total (n = 425) | Patients without eosinophilia (n = 338) | Patients with eosinophilia (n = 87) | P value | |
|---|---|---|---|---|
Peripheral blood eosinophil count (cells per μL) | 210 (100–420) | 170 (80–260) | 770 (610–1100) | <0.001 |
Age (years)# | 54 ± 13 | 54 ± 13 | 53 ± 15 | 0.442 |
Male (%) | 60.4% | 57.1% | 73.3% | 0.007 |
Disease duration (months)* | 12(4–36) | 10(4–36) | 12(6–48) | 0.034 |
Allergy history | 49.2% | 47.6% | 55.2% | 0.145 |
IgG4-RD RI* | 12 (7–16) | 11 (7–15) | 13 (10–17) | <0.001 |
Numbers of organs involved | 3.31 ± 1.71 | 3.17 ± 1.63 | 3.86 ± 1.89 | 0.003 |
HBG (g/L)# | 134.2 ± 18.3 | 134.2 ± 18.1 | 134.3 ± 19.2 | 0.687 |
PLT (×109/L)* | 231 (195–280) | 231 (191–281) | 237 (206–278) | 0.254 |
WBC (×109/L)* | 6.7 (5.6–8.0) | 6.5 (5.5–7.7) | 7.32 (5.90–9.03) | <0.001 |
ESR (mm/h)* | 18 (8–51) | 17 (8–44) | 34 (12–76) | 0.002 |
CRP (mg/L)* | 2.1 (0.8–7.6) | 2.3 (0.7–7.6) | 2.1 (1.3–7.4) | 0.342 |
IgG (g/L)* | 18.7 (14.6–24.7) | 18.1 (14.2–23.3) | 24.1 (16.4–32.6) | <0.001 |
IgA (g/L)* | 2.06 (1.39–2.75) | 2.14 (1.54–2.85) | 1.54 (0.96–2.13) | <0.001 |
IgM (g/L)* | 0.77 (0.55–1.22) | 0.81 (0.57–1.24) | 0.70 (0.48–1.05) | 0.094 |
IgG1 (g/L)* | 9.14 (7.45–11.00) | 9.06 (7.30–10.60) | 9.68 (7.65–13.10) | 0.009 |
IgG2 (g/L)* | 5.73 (4.42–7.58) | 5.88 (4.56–7.64) | 5.27 (3.75–7.18) | 0.022 |
IgG3 (g/L)* | 0.45 (0.24–0.86) | 0.42 (0.23–0.81) | 0.55 (0.31–0.98) | 0.012 |
IgG4 (g/L)* | 7.72 (3.18–17.50) | 6.50 (2.74–14.38) | 17.00 (5.60–31.55) | <0.001 |
IgG4/IgG* | 0.34 (0.17–0.53) | 0.31 (0.16–0.48) | 0.49 (0.25–0.61) | <0.001 |
IgE (KU/L)* | 347 (126–752) | 302 (119–662) | 480 (157–1164) | 0.010 |
C3 (g/L)* | 0.94 (0.75–1.11) | 0.96 (0.79–1.11) | 0.79 (0.58–1.15) | 0.088 |
C4 (g/L)* | 0.17 (0.12–0.24) | 0.18 (0.13–0.24) | 0.12 (0.05–0.19) | <0.001 |
