Table 1 Hyperuricemia and cardiovascular disease risk factors in SHFS.
Phenotype* | Normouricemia | Hyperuricemia** | P value |
|---|---|---|---|
Anthropometric | |||
Body weight (kg) | 88.08 (24.1) | 97.79 (23.8) | <0.0001 |
Waist circumference (cm) | 103.57 (18.8) | 107.59 (18.0) | <0.0001 |
BMI (kg/m2) | 33.04 (8.2) | 34.38 (7.3) | NS |
Lipids | |||
Total cholesterol (mg/dl) | 177.46 (34.6) | 189.74 (42.3) | <0.0001 |
HDL cholesterol (mg/dl) | 51.56 (14.6) | 48.26 (14.1) | <0.0001 |
LDL cholesterol (mg/dl) | 95.92 (28.1) | 104.39 (31.8) | <0.0001 |
Triglycerides (mg/dl) | 156.65 (129) | 200.44 (254) | <0.0001 |
ECHO measures | |||
Heart rate (BPM) | 66.99 (10.6) | 67.38 (11.5) | NS |
Left ventricular mass (g) | 152.72 (39.0) | 175.27 (41.7) | <0.0001 |
Relative wall thickness | 0.298 (0.04) | 0.301 (0.04) | 0.030 |
Stroke volume (ml) | 80.81 (14.5) | 84.90 (15.1) | <0.0001 |
Ejection fraction | 60.41 (5.7) | 58.63 (5.8) | <0.0001 |
Cardiac output (ml/min) | 5376.44 (1153) | 5673,0.78 (1252) | <0.0001 |
Total peripheral resistance (dyne/cm/sec) | 1410.02 (304) | 1392.27 (316) | NS |
Blood pressure | |||
Systolic (mmHg) | 121.25 (17.2) | 126.56 (15.8) | <0.0001 |
Diastolic (mmHg) | 75.47 (11.0) | 78.46 (11.6) | <0.0001 |
Carotid measures | |||
Left common carotid diastolic diameter (mm) | 5.67 (0.7) | 6.00 (0.7) | <0.0001 |
Right common carotid diastolic diameter (mm) | 5.78 (0.7) | 6.10 (0.7) | <0.0001 |
Left common carotid systolic diameter (mm) | 6.40 (0.7) | 6.78 (0.7) | <0.0001 |
Right common carotid systolic diameter (mm) | 6.51 (0.7) | 6.87 (0.8) | <0.0001 |
Left common carotid artery intimal medial thickness (mm) | 0.66 (0.2) | 0.69 (0.2) | <0.0001 |
Right common carotid artery intimal medial thickness (mm) | 0.66 (0.2) | 0.68 (0.2) | 0.003 |
