Table 3 Variants associated with serum urate in meta-analysis of the three centers.

From: Fine mapping and identification of serum urate loci in American Indians: The Strong Heart Family Study

SNP

Allele1

Allele2

Zscore

P-value

Direction

Gene

Gene loc

Chr

Chr pos hg18

rs4481233

A

G

−9.28

1.7 × 10−20

—

SLC2A9

Intron

4

9956079

rs9998811*

A

G

−9.02

1.8 × 10−19

—

SLC2A9

Intron

4

9966477

rs7696092

A

C

7.78

7.2 × 10−19

+++

SLC2A9

Intron

4

10025320

rs13145758*

A

G

8.98

2.8 × 10−14

+++

SLC2A9

Intron

4

9981997

rs4148155*

A

G

−5.98

2.2 × 10−09

—

ABCG2

Intron

4

89054667

rs2231142*

A

C

5.94

2.8 × 10−09

+++

ABCG2

Missense

4

89052323

rs1481012*

A

G

−5.94

2.9 × 10−09

—

ABCG2

Intron

4

89039082

  1. *SNPs are in linkage disequilibrium (LD; r2 > 0.90); SNP: single nucleotide polymorphism; P-value: P-values from meta-analysis; Gene loc: Gene location; Chr pos: chromosome position in base pairs; SLC2A9: solute carrier family 2, member 9; ABCG2: ATP-binding cassette family G, member 2.
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