Table 1 Motor cortex metabolite ratios.

From: Short echo-time Magnetic Resonance Spectroscopy in ALS, simultaneous quantification of glutamate and GABA at 3 T

 

Healthy subjects (n = 10), mean (SD)

ALS Subjects (n = 9), mean (SD)

p-value

tNAA/Cr

1.62 (0.12)

1.46 (0.18)

0.034*

Glutamate/Cr

0.983 (0.10)

0.809 (0.11)

0.002*

Glutamine/Cr

0.246 (0.05)

0.242 (0.04)

0.860

GABA/Cr

0.312 (0.06)

0.279 (0.02)

0.113

Glutathione/Cr

0.166 (0.02)

0.187 (0.02)

0.040*

Myo-inositol/Cr

0.723 (0.12)

0.832 (0.16)

0.100

tCho/Cr

0.203 (0.04)

0.238 (0.03)

0.042*

Cr+PCr/water

6.26 (0.52)

5.79 (0.70)

0.11

  1. *Significant using a Students two-tailed t-test p < 0.05.
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