Figure 2

Assessments of fecal metagenome functions with 16S-rRNA. (A) PCAs were conducted on profiles of KEGG functional pathways, as inferred by Piphillin with 16S rRNA sequences. Samples before (circles) and 1 month after (triangles) CBM588 ingestion were plotted. Each patient was designated a specific color. In most patients, apparent shifts after 1 month of exposure were noted. (B) Radar plots of 10 rarefactions are prepared with pointing hands as model coefficients from support vector classification and logistic regression, respectively. ko00511 was one and the only pathway agreed by both models. (C) Percentages of the ko00511 pathway among 10 rarefied data sets of all samples collected before or 1 month after CBM588 ingestion are plotted. Red lines connect the same patients. Variations between rarefied data sets were minimal. Nearly all patients had upward trends for the ko00511 pathway.