Table 2 Stability determination of ifosfamide (IF) under various storage conditions.
From: Pharmacokinetic parameters of ifosfamide in mouse pre-administered with grapefruit juice or naringin
Storage conditions | Concentration (μg/mL) | RSD (%) | RE (%) | |
|---|---|---|---|---|
Added | Found | |||
Short-term (24 h, 25 °C) | 10 | 12.31 ± 0.68 | 5.39 | −11.66 |
90 | 100.11 ± 14.27 | 14.26 | 0.04 | |
Long-term (30 days, −70 °C) | 10 | 11.17 ± 0.53 | 4.77 | −6.18 |
90 | 108.34 ± 1.64 | 1.51 | −11.15 | |
Freeze and thaw stability (−70 to 25 °C) | 10 | 11.16 ± 0.11 | 0.99 | −1.82 |
90 | 81.34 ± 4.99 | 6.14 | 18.78 | |
