Figure 6

ECM niche modulates hAEC secretion of pro-inflammatory cytokines. Expression levels of (A) TNF-α, (B) IL-8, and (C) IL-6 exhibited an overall higher expression level on the serous side compared to the fibrous side of AR-BP scaffolds with significant increases observed after 4 days of culture at an initial seeding density of 142 cell/mm2. Each column represents concentration normalized to cell proliferation ± SD, n = 7; (**p < 0.01, *p < 0.05).