Table 1 Top downstream targets of CBX2.1 and CBX2.2 obtained from DamID and RNA-seq data.
Gene symbol | −log10(p-value) | Fold enrichment | Gene symbol | log2 Ratio | fdr | p-Value |
|---|---|---|---|---|---|---|
CBX2.1 DamID | CBX2.1 RNA-seq | |||||
MYC | 83.89999 | 8.48561 | RNA5-8S5 | -4.289 | 8.71E-07 | 0.001152 |
CBX2 | 14.52065 | 7.43178 | RNA5-8S5 | -4.074 | 8.63E-07 | 0.001152 |
PCDH9 | 14.07725 | 8.75539 | CYP19A1 | 2.524 | 3.04E-07 | 0.0005027 |
MIR1258 | 14.07725 | 8.75539 | ESM1 | 1.448 | 2.83E-07 | 0.0005027 |
GRHL2 | 14.07725 | 8.75539 | PSMA1 | 2.349 | 2.49E-07 | 0.0005027 |
LOC100130331 | 14.07725 | 8.75539 | COL3A1 | -1.482 | 1.51E-07 | 0.0004006 |
TTC39C | 13.25753 | 8.31353 | ACTA2 | -1.296 | 1.50E-07 | 0.0004006 |
YTHDC1 | 12.90472 | 7.73385 | PLIN2 | 1.423 | 1.05E-07 | 0.0004006 |
RCBTB2 | 12.64768 | 8.0819 | ANGPTL4 | 3.349 | 1.81E-24 | 1.19E-20 |
LOC338862 | 12.64768 | 8.0819 | CBX2 | 9.212 | 1.93E-59 | 2.55E-55 |
CBX2.2 DamID | CBX2.2 RNA-seq | |||||
LMNB1 | 13.63833 | 8.52171 | MS4A4E | 2.273 | 1.274E-36 | 0.00507 |
C6orf105 | 13.63833 | 8.52171 | RP11-512M8.5 | 1.945 | 1.534E-21 | 0.003451 |
ATP6V1H | 13.63833 | 8.52171 | ANGPTL4 | 1.847 | 1.629E-20 | 0.002252 |
TRPC7 | 13.41263 | 8.24715 | SHANK1 | 5.793 | 1.629E-20 | 0.001976 |
LOC151162 | 13.36989 | 8.22215 | NYNRIN | -4.972 | 1.629E-20 | 0.001862 |
PCDH9 | 12.24367 | 7.86619 | HPCAL4 | 5.927 | 1.543E-19 | 0.001322 |
LPHN2 | 12.24367 | 7.86619 | UQCR11 | 2.075 | 1.543E-19 | 0.001226 |
EPS8L3 | 12.24367 | 7.86619 | DNASE1L2 | 6.34 | 5.678E-19 | 0.0003375 |
LOC151658 | 12.24367 | 7.86619 | C4orf48 | 2.908 | 7.747E-19 | 0.0001456 |
RHO | 12.24367 | 7.86619 | CBX2 | 6.879 | 5.923E-18 | 2.66E-17 |
