Figure 5 | Scientific Reports

Figure 5

From: 2, 3-Dihydro-3β-methoxy Withaferin-A Lacks Anti-Metastasis Potency: Bioinformatics and Experimental Evidences

Figure 5

Wi-A, and not 3βmWi-A, inhibited hnRNP-K at protein levels. (a) Immunoblot showing hnRNP-K expression in control, 0.3 μM, and 0.6 μM Wi-A and 3βmWi-A (cropped blot omitting their 1.5, and 3 μM toxic doses) treated U2OS cancer cells; quantitation of its expression is shown in the lower panel. (b) Immunostaining showing hnRNP-K expression in the treated cells; quantitation of its expression is shown at the bottom. (c) RT-PCR showing hnRNP-K transcript in the treated cells; quantitation of its expression is shown in the lower panel.

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