Figure 6 | Scientific Reports

Figure 6

From: Aluminosilicate Nanocomposite on Genosensor: A Prospective Voltammetry Platform for Epidermal Growth Factor Receptor Mutant Analysis in Non-small Cell Lung Cancer

Figure 6

(a) Voltammetry signal generated by DNA hybridization. Performed with mutant, wild and non-complementary strands justifying the specificity of genosensor in the detection of EGFR mutation in the presence of single base pair mismatch. (b) I-V characteristics generated at every step of functionalization demonstrated the influence of chemical bonding on electron flow through the electrodes. (c) The curve represents the voltammetry response amplified by genosensor at different concentration of mutant strand at 2 V. (d) Graph plotted shows the relative change of current against the different concentration of mutant at 2 V, revealing the detection limit (LOD).

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