Figure 4 | Scientific Reports

Figure 4

From: Induction of HLA-A2 restricted CD8 T cell responses against ApoB100 peptides does not affect atherosclerosis in a humanized mouse model

Figure 4

Vaccination with ApoB100 peptides does enhance CD8 T cell levels but not reactivity towards ApoB100 peptides in the aortic root (A) Quantification of CD8 T cell percentage in aortic cultures. (B) Representative flow cytometry plots of aortic CD8 T cell activation and (C) quantification of IFN-γ and TNF-α double positive cell % from CD8 T cells after restimulation with a mix of all peptides. Statistical analysis was performed with 1-way ANOVA and Tukey’s multiple comparisons test. Depicted as mean with SEM, *P < 0.05.

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