Figure 2 | Scientific Reports

Figure 2

From: Dissection of major cancer gene variants in subsets of circulating tumor cells in advanced breast cancer

Figure 2

Distribution of CTC subsets. Magnitude of EMT-related CTCs from metastatic BC patients, grouped as A (treatment-naïve) or B (pre-treated). The upper section depicts percent values of these cohorts with significant differences regarding both M+/E− and M−/E− subsets. The lower part shows the extent of all CTC subsets in each patient depicting intra- and inter-patient heterogeneity, even within the same group of patients. The numbers in brackets are the recovered CTCs from each patient (range: 7–106). Abbreviations: CTCs: circulating tumor cells; M+/E−: CTCs expressing only M markers; M−/E−: CTCs negative for both M and E markers; M+/E+: CTCs expressing both M and E markers; M−/E+: CTCs expressing only E markers.

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