Table 2 Number and phenotype of CTCs recovered from each patient, classified as treatment-naïve (A) or pre-treated (B), by DEPArray separation.

From: Dissection of major cancer gene variants in subsets of circulating tumor cells in advanced breast cancer

Patient code

M+/E−

M−/E−

M+/E+

M−/E+

A) Treatment-naїve patients

274

5

0

2

0

337

69

0

14

0

372

9

0

31

5

382

33

6

5

0

392

58

2

0

0

407

57

8

12

0

454

23

6

0

0

Mean value

36.28

3.14

9.14

0.71

Median value

33

2

5

0

B) Pre-treated patients

123

3

0

4

0

242

9

6

9

2

253

0

20

39

8

279

22

14

12

0

335

43

0

0

14

371

6

3

0

0

399

42

34

0

0

431

60

46

0

0

458

6

6

0

0

471

29

13

8

0

Mean value

22

14.2

7.2

2.4

Median value

15.5

9.5

2

0

Total

474

164

136

29

Median value

23

6

4

0

  1. Abbreviations: M+/E−: CTCs expressing only mesenchymal markers; M−/E−: CTCs which do not express either mesenchymal or epithelial markers; M+/E+: CTCs expressing both mesenchymal and epithelial markers; M−/E+: CTCs expressing only epithelial markers.