Table 3 Comparisons among groups at baseline and assessment of injury severity.
Vehicle, n = 16 | FPLT, n = 8 | PEVs, n = 8 | ANOVA | ||||
|---|---|---|---|---|---|---|---|
Mean | SEM | Mean | SEM | Mean | SEM | p value | |
(A) Baseline values | |||||||
Body weight (g) | 338± | 5 | 351± | 8 | 334± | 3 | 0.17 |
Blood volume (mL) | 22± | 0.3 | 23± | 0.5 | 22± | 0.2 | 0.17 |
MAP (mmHg) | 104± | 1 | 103± | 1 | 101± | 2 | 0.33 |
Hematocrit (%) | 42.7± | 0.8 | 44.5± | 1.4 | 44.6± | 1.4 | 0.33 |
Plasma protein(g/dL) | 4.6± | 0.1 | 5.3± | 0.3 | 4.7± | 0.2 | 0.09 |
Lactate (mmol/L) | 0.6± | 0.0 | 0.6± | 0.1 | 0.6± | 0.1 | 0.96 |
BE (mmol/L) | 5.3± | 0.7 | 2.7± | 1.0 | 6.3± | 0.8 | 0.08 |
CO2 (mmHg) | 47± | 3 | 46± | 3 | 44± | 1 | 0.10 |
O2 (mmHg) | 509± | 28 | 474± | 38 | 499± | 33 | 0.80 |
pH | 7.4± | 0.0 | 7.4± | 0.0 | 7.4± | 0.0 | 0.18 |
(B) Injury Severity parameters | |||||||
Excised Liver (g) | 1.2± | 0.1 | 1.1± | 0.0 | 1.1± | 0.1 | 0.31 |
Bleeding Surface (cm2) | 1.9± | 0.1 | 1.7± | 0.1 | 1.9± | 0.1 | 0.12 |
MAP-1 min (mmHg) | 51± | 6 | 52± | 6 | 63± | 6.4 | 0.39 |