Table 4 Treatment effects on blood parameters and tissue water content.

From: Platelet-derived- Extracellular Vesicles Promote Hemostasis and Prevent the Development of Hemorrhagic Shock

 

Vehicle, n = 16

FPLT, n = 8

PEVs, n = 8

ANOVA

Mean

SEM

Mean

SEM

Mean

SEM

p value

Hematocrit (%)

31±

1

29±

1

29±

2

0.47

Plasma protein (g/dL)

3±

0.1

3±

0.1

4±

0.1

0.048*

Lactate (mmol/L)

5±

1

3±

1

1±

0

0.002*

BE (mmol/L)

−2.9±

2.3

−5.6±

2.7

3.5±

0.8

0.013*

CO2 (mmHg)

46±

5

45±

5

56±

10

0.52

O2 (mmHg)

337±

51

341±

97

515±

68

0.12

Lung (Index)

3.9±

0.17

3.9±

0.04

3.9±

0.04

0.95

Heart (Index)

3.4±

0.08

3.3±

0.03

3.3±

0.05

0.55

Liver (Index)

2.4±

0.04

2.4±

0.06

2.2±

0.03

0.07

Kidney (Index)

2.8±

0.09

2.6±

0.10

2.8±

0.10

0.36

  1. Gasometry and protein concentration measured from blood following 60 min of injury and treatment. Lung, heart, liver and kidney water content was determined by W/D index. Data reported as mean ± SEM and compared by 1-way ANOVA, * p < 0.05 vs. Control.
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