Figure 1
From: β-Cyclodextrin counteracts obesity in Western diet-fed mice but elicits a nephrotoxic effect
2HP-β-CD prevents weight gain and the accumulation of adipose tissue. Evaluation of weight gain, caloric intake and adipose tissue. (a) Body weight was monitored for 16 weeks in each experimental group. (b) Food intake measured as kcal/mouse/day. (c) Plasma cholesterol levels. (d–f) EWAT, perirenal and pararenal fats were weighed upon sacrifice and are shown as a percentage of total body weight. CD = control diet; VEH = vehicle; WD = western diet; CYCLO = 2HP-β-CD; kcal = kilocalorie; Chol = cholesterol; EWAT = epididymal white adipose tissue. Data shown as mean ± SEM. Statistical analysis of plasma chol, EWAT, perirenal and parerenal fat pads was performed using the One-way ANOVA test with Bonferroni post-hoc analysis. Statistical analysis of food intake was performed using the Kruskal Wallis test with Dunn’s post hoc analysis. *p > 0.05, **p > 0.01, *** p > 0.001.
