Table 1 Effect of Core and Core/shell NSs on transcriptional activity of lasR and pqsA.

From: Mitigation of acyl-homoserine lactone (AHL) based bacterial quorum sensing, virulence functions, and biofilm formation by yttrium oxide core/shell nanospheres: Novel approach to combat drug resistance

Concentration (µg/mL)

Core-NSs

Core/shell NSs

lasR

pqsA

lasR

pqsA

Control

943 ± 34.6

1042 ± 23.4

943 ± 34.6

1042 ± 23.4

25

859 ± 21.2

881 ± 36.8

799 ± 24.4

724 ± 31.9

50

714 ± 28.8

635 ± 27.9*

680 ± 38.8

503 ± 43.3*

100

601 ± 42.1*

517 ± 38.2*

536 ± 34.6*

389 ± 48.1**

200

556 ± 34.7*

365 ± 37.1**

424 ± 44.3**

344 ± 31.9**

  1. Transcriptional activity was measured via β -galactosidase activity of the lacZ gene fusion products and expressed as Miller Units. *Indicates significance at p < 0.05. **Indicates significance at p < 0.005.
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