Figure 3
From: A common root for coevolution and substitution rate variability in protein sequence evolution
Panel (a): estimated α by the model described by Eq. 1 and by the two-class model as a function of the sequence identity. The value of α is estimated by fitting the number of substitutions per site to a negative binomial (Eq. 2). Panel (b): Estimate of α for five Pfam families obtained by FastTree-249 on subtrees characterized by different average sequence identities (procedure described in Materials and Methods).
