Figure 7

Blocking TNF-α prevents cancellous bone loss in FcγRIIB^−/− mice. (A) Representative μCT images of the tibial cancellous bone from WT and FcγRIIB^−/− males treated with either PBS or etanercept. (B) μCT analysis of the proximal tibial metaphysis. Results are mean ± SEM. ^ap < 0.05 versus WT controls treated with PBS, ^bp < 0.05 versus WT controls treated with etanercept, and ^cp < 0.05 versus FcγRIIB^−/− mice treated with PBS.