Table 1 Summary of all the significant values from the calibration performed using bare and nanostructured SPEs (LOD and LOQ are expressed in µg/ml, while sensitivities are expressed in µa/(µg/ml)).
From: Electrochemical detection of different p53 conformations by using nanostructured surfaces
Bare SPEs | Nanostructured SPEs | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
range 1–8 µg/ml | range 0.1–2 µg/ml | range 1–8 µg/ml | ||||||||
Sensitivity | LOD | LOQ | Sensitivity | LOD | LOQ | Sensitivity | LOD | LOQ | ||
CATHODIC PEAK | C | 2.86 ± 0.83 | 1.60 ± 0.02 | 5.33 ± 0.06 | 15.08 ± 3.33 | 0.55 ± 0.13 | 1.83 ± 0.43 | 14.74 ± 3.57 | 0.57 ± 0.15 | 1.9 ± 0.5 |
Pt | 1.94 ± 0.62 | 1.85 ± 0.05 | 6.16 ± 0.16 | 42.13 ± 7.00 | 0.20 ± 0.02 | 1 ± 0.4 | 10.72 ± 2.6 | 1.10 ± 0.26 | 3.66 ± 0.86 | |
Pt Act | 3.79 ± 1.56 | 0.90 ± 0.15 | 3 ± 0.5 | 28.47 ± 6.28 | 0.23 ± 0.05 | 0.76 ± 0.17 | 8 ± 4.26 | 0.74 ± 0.66 | 2.46 ± 2.2 | |
ANODIC PEAK | C | 2.64 ± 0.61 | 1.71 ± 0.03 | 5.7 ± 0.10 | 20.53 ± 7.79 | 0.54 ± 0.18 | 1.8 ± 0.6 | 19.7 ± 6.88 | 0.58 ± 0.20 | 1.93 ± 0.66 |
Pt | 8.62 ± 2.14 | 0.86 ± 0.04 | 2.86 ± 0.13 | 39.01 ± 5.88 | 0.17 ± 0.06 | 0.57 ± 0.2 | 21.11 ± 3.92 | 0.29 ± 0.06 | 0.96 ± 0.2 | |
Pt Act | 14.47 ± 4.23 | 0.52 ± 0.12 | 1.73 ± 0.4 | 38.74 ± 11.19 | 0.25 ± 0.13 | 0.83 ± 0.43 | 14.17 ± 13.2 | 0.76 ± 1.02 | 2.53 ± 3.4 | |
ASV PEAK | C | 20.90 ± 5.23 | 1.00 ± 0.30 | 3.33 ± 1.00 | 15.31 ± 9.16 | 0.19 ± 0.07 | 0.63 ± 0.23 | 27.01 ± 8.81 | 0.18 ± 0.07 | 0.6 ± 0.23 |
Pt | 8.82 ± 2.85 | 1.34 ± 0.44 | 4.46 ± 1.46 | 29.32 ± 5.86 | 0.11 ± 0.02 | 0.33 ± 0.06 | 21.68 ± 4.79 | 0.17 ± 0.04 | 0.57 ± 0.13 | |
Pt Act | 14.71 ± 1.38 | 0.52 ± 0.05 | 1.73 ± 0.16 | 37.83 ± 10.70 | 0.18 ± 0.06 | 0.56 ± 0.3 | 20.64 ± 1.51 | 0.35 ± 0.03 | 1.16 ± 0.1 | |
