Figure 5
Blood pressure (BP) responses to stimulation of different DCNs at different stimulation frequencies. Traces show averaged (n = 24, 8 animals and 3 segments combined) BP data, all evoked at 5 mA stimulation strength. Stimulation of combined rostral (T6-T8), middle (T9-T11), and caudal (T12-L1) DCNs at all frequencies (1, 2, 5, and 10 Hz) are shown. On the plots, the magenta line represents the mean, the dark gray area represents the standard deviation above/below the mean, and the light gray area represents the range between minimal and maximal values at each time point in the response. The line at the bottom of the panels indicated DCN stimulation time (Stim). The BP data was summarized by the change per second in the response over the response phases described in the methods. Statistical analysis was performed along the panels on the right and bottom. The right panels compared responses from different DCN groups at different frequencies, and the bottom panels compared responses across stimulation frequencies at different DCN groups. In all cases, ANOVA was used to evaluate if the data came from the same statistical distribution (*p < 0.05, **p < 0.01, ***p < 0.001), and Cohen’s D was used to find the effect size for those with statistically significant differences of p < 0.01. Cohen’s D was calculated between the largest and smallest mean responses in those sets and is displayed under the p values. Error bars show standard deviation.
