Figure 4
From: Development of a diagnostic compatible BCG vaccine against Bovine tuberculosis
Protective efficacy of ΔBCG TK vaccination in Guinea pigs upon M. bovis challenge. (a) The bacterial load in the lungs of WT BCG (P = 0.0021) and ΔBCG TK (P = 0.0006) vaccinated guinea pigs is significantly low compared to the with the unvaccinated control group. (b) The bacterial load in spleen of WT BCG (P = 0.0015) and ΔBCG TK (P = 0.0006) vaccinated guinea pigs is significantly low compared to the unvaccinated control group. Values for each individual are shown and the horizontal bar denotes the mean for each group. *P = ≤ 0.05, P = ≤ 0.01, ***P = ≤ 0.001.
