Figure 7
(A) Small molecules (Nutlin 3A, MI-773 and RO-5963) and (B) either VIP-82 or VIP82SCRAM were titrated onto CHO-K1 cells for periods of either 4 or 24 hours and their resulting LDH profiles were assessed. Experiments were performed in DMEM media containing 2% FCS (v/v) with respect to the VIP-82 analogues and 10% in the case of the small molecules.
