Table 3 ρ-TIA potency at hamster and zebrafish α1-adrenoceptors. IC50 ± SEM values (n = 3–6) are shown.
From: The α1-adrenoceptor inhibitor ρ-TIA facilitates net hunting in piscivorous Conus tulipa
Receptor | Radioligand binding assay (nM) | IP-one functional assay (μM) |
|---|---|---|
Hamster α1B | 4.39 ± 0.14 (3) | 1.56 ± 0.17 (3) |
Zebrafish α1BB | 3198.9 ± 46.26 (3) | 15.26 ± 1.19 (6) |
Zebrafish α1BB E327D/S330F | 88.51 ± 11.14 (3) | 2.61 ± 0.22 (4) |
