Table 2 Demographics and clinical characteristics of reactional patients recruited longitudinally§.

From: Whole blood RNA signatures in leprosy patients identify reversal reactions before clinical onset: a prospective, multicenter study

#

area

RJ

LR

BI*

PGL-I*

sex

age*

1

Bangladesh

BL

RR

2+

0.95

male

36

2

Bangladesh

BL

RR

2+

0.27

female

39

3

Bangladesh

BL

RR

0

1.82

male

36

4

Bangladesh

BL

RR

2+

1.17

male

32

5

Brazil

BL

RR

3.2+

0,43

male

35

6

Brazil

BL

RR

2.42+

0.07

male

29

7

Brazil

BL

RR

4.28+

1.02

female

42

8

Nepal

BT

RR

0.25+

0.07

female

40

9

Ethiopia

BB

RR

0

0.15

male

33

10

Netherlands

BL

RR

5+

1.83

male

17

  1. §Blood samples were collected from 10 patients at 3 time points: at diagnosis of leprosy in the absence of any clinical signs of reactions, at diagnosis of reactions and after treatment; * at recruitment before treatment.
  2. RJ: Ridley Joplin classification; LR: Leprosy Reaction; RR: reversal reaction.
  3. BI: bacterial index; PGL-I: OD at 450 nm in anti-PGL-I antibody ELISA (threshold for positivity: OD450 = 0.2).