Figure 5

RSV reduces granzyme production in IL-21-treated human CD8 T cells. Human memory CD8 T cells were isolated from PBMCs, incubated with RSV for 1 h and stimulated with IL-21 for 4 h Granzyme B production was analyzed by flow cytometry. (A) Representative flow cytometry plots from memory CD8 T cells positive for granzyme B. (B) Percentage of memory CD8 granzyme B+ cells. (C) MFI of granzyme B+ cells. Statistical significance was determined using the Friedman test followed by the Dunn posttest.