Table 1 Clinical characteristics of the children involved in the current study.
From: Cytokine signatures associate with disease severity in children with Mycoplasma pneumoniae pneumonia
Control | Mild MPP | Severe MPP | Control vs. Mild | Control vs. Severe | Mild vs. Severe | |
|---|---|---|---|---|---|---|
(n = 26) | (n = 45) | (n = 43) | p value | p value | p value | |
Gender (female/male) | 8/18 | 22/23 | 13/30 | 0.1411 | 0.969 | 0.0763 |
Median age (range), years | 1.83 (0.92–3) | 5 (1.67–12) | 6 (1.75–13) | <0.0001*** | <0.0001*** | 0.9162 |
Fever duration, days | — | 8.84 ± 4.67 | 10.58 ± 4.23 | — | — | 0.0089** |
Glucocorticoid (yes/no) | 0/26 | 7/38 | 27/16 | 0.0365* | <0.0001*** | <0.0001*** |
Pleural effusion (yes/no) | 0/26 | 2/43 | 11/32 | 0.5292 | 0.0048* | 0.0056** |
Extrapulmonary manifestations (yes/no) | 0/26 | 0/45 | 2/41 | >0.9999 | 0.2772 | 0.3458 |
Median CRP (range), mg/L | — | 19.04 ± 23.96 | 34.57 ± 40.1 | — | — | 0.0057** |
Peripheral blood cell count | ||||||
Blood leukocyte count (×109 cells/L) | — | 8.59 ± 3.17 | 9.6 ± 4.83 | — | — | 0.7134 |
Blood monocyte count (%) | — | 8 (3–13) | 7 (2–12) | — | — | 0.3683 |
Blood neutrophil count (%) | — | 59 (20–86) | 68 (48–89) | — | — | 0.0031** |
Blood lymphocyte count (%) | — | 29 (11–70) | 22 (9–39) | — | — | 0.0021** |
Blood eosinophil count (%) | — | 2 (0–5) | 2 (0–5) | — | — | 0.7268 |
Indication of bronchoscopy | ||||||
Diagnosis and remove of bronchus foreign body | 18 | 0 | 0 | — | — | — |
Re-examination of bronchus foreign body | 8 | 0 | 0 | — | — | — |
Diagnosis and treatment of lobar pneumonia | 0 | 16 | 43 | — | — | — |
Diagnosis and treatment of segmental pneumonia | 0 | 29 | 0 | — | — | — |
Timing of BALF collection | ||||||
Before treatment | 26 | 45 | 43 | — | — | — |
After the treatment | 0 | 0 | 0 | — | — | — |
