Table 2 Pharmacokinetic parameters according to metabolizer phenotype.

7

9

12

8

11.07 ± 3.49^a

7.21 ± 0.91^a

6.51 ± 1.16^a

4.12 ± 0.89^a

45.84 ± 14.69^b

34.98 ± 2.13^b

26.44 ± 2.87^b

15.30 ± 3.74^b

51.61 ± 15.59^c

43.17 ± 10.58^c

32.87 ± 2.96^c

21.62 ± 4.67^c

0.2013 ± 0.0431

0.2063 ± 0.0708

0.1794 ± 0.0452

0.1880 ± 0.0577

3.58 ± 0.80

4.01 ± 1.15

4.11 ± 1.15

3.96 ± 1.08

1.53 ± 0.32^d

1.80 ± 0.31^d

2.30 ± 0.20^d

3.64 ± 0.91^d

7.89 ± 2.13^e

9.59 ± 2.87^e

13.68 ± 4.08^e

19.90 ± 3.75^e