Table 2 Physiologic parameters for 39 male NGR [separated at 3 wks old] fed a semi-purified high carbohydrate diet (60:20:20) with or without 10% PFB for 8 weeks, then subdivided into resistant or susceptible to diabetes based on a random blood glucose (RBG) ≥ 75 mg glucose/100 ml plasma.

CHO:Fat:Prot %E

kcal/g

mg GAE/kcal

mg GAE/g diet

resistant

susceptible

resistant

susceptible

<75 mg

>75 mg

<75 mg

>75 mg

RBG >75 mg/dl

(% incidence T2DM) n=

9

12 (66%)

12

6 (33%)

Initial (3wk of age)

28 ± 3

28 ± 4

28 ± 4

30 ± 6

After 4 wks

71 ± 8

78 ± 6^a

70 ± 7^a

74 ± 9

After 8 wks

92 ± 5

97 ± 7^a

90 ± 9^a,b

99 ± 8^b

After 4 wks

68 ± 6^a

125 ± 88^a,b

76 ± 17^b

89 ± 34

After 8 wks

63 ± 5^a

268 ± 209^a,b

63 ± 7^b

163 ± 162

  Fasting blood glucose, 0 min

55 ± 25

54 ± 18

57 ± 9

46 ± 6

30 min

230 ± 48

261 ± 43^a

198 ± 59^a

221 ± 79

  Fasting blood glucose, 0 min

47 ± 8

59 ± 27

57 ± 11

55 ± 12

    30 min

182 ± 27^a,b,c

372 ± 101^a,d,e

263 ± 63^b,d

306 ± 94^c,e

    60 min

97 ± 32^a,b

269 ± 141^a,c

165 ± 48^c

202 ± 112^b

Liver

3.16 ± 0.26^a

3.80 ± 0.55^a,bc

3.46 ± 0.20^b

3.43 ± 0.22^c

Kidne

0.66 ± 0.05^a

0.73 ± 0.07^a

0.70 ± 0.04

0.72 ± 0.11

Cecum

1.16 ± 0.12^a,b

1.29 ± 0.28^c,d

1.64 ± 0.40^a,c

1.58 ± 0.15^b,d

      Epididymal

3.31 ± 0.48^a,b

2.86 ± 0.38^a

2.81 ± 0.50^b

3.07 ± 0.40

      Perirenal

1.54 ± 0.19

1.69 ± 0.52

1.56 ± 0.40

1.64 ± 0.38

      Brown fat

1.73 ± 0.36

2.00 ± 0.34

1.88 ± 0.41

2.05 ± 0.31

        Total fat

6.59 ± 0.64

6.56 ± 1.04

6.26 ± 1.05

6.76 ± 0.49

    Carcass

75 ± 1

76 ± 7

74 ± 1

74 ± 1

Body length (cm)

12.9 ± 0.5

13.4 ± 0.6^a

12.9 ± 0.6^a

13.3 ± 0.5