Table 1 Identified potential biomarkers of cecal samples between the control and RSB treatment groups.

From: Integrative analysis of the gut microbiota and metabolome in rats treated with rice straw biochar by 16S rRNA gene sequencing and LC/MS-based metabolomics

Metabolites

RT(min)

m/z

VIP

Formula

Trend

Related pathway

L-Phenylalanine

3.56

148

1.90

C9H11NO2

↑**

Phenylalanine metabolism

L-Glutamate

4.30

130

1.24

C5H9NO4

↑**

Arginine biosynthesis

L-Isoleucine

0.80

132

2.37

C6H13NO2

↓*

Valine, leucine and isoleucine metabolism

3-Phenylpropanoic acid

6.87

151

1.88

C9H10O2

↑**

Phenylalanine metabolism

Benzoic acid

6.44

123

1.57

C7H6O2

↓**

Phenylalanine metabolism

Chenodeoxycholic acid

8.27

415

1.64

C24H40O4

↑**

Primary bile acid biosynthesis

Indole-3-acetic acid

4.75

176

1.02

C10H9NO2

↓**

Tryptophan metabolism

Tetradecanoic acid

4.25

267

2.30

C14H28O2

↓**

Fatty acid biosynthesis

Cholic acid

8.15

391

1.53

C24H40O5

↑**

Primary bile acid biosynthesis

7-Dehydrocholesterol

9.70

385

1.97

C27H44O

↑**

Steroid biosynthesis

(5Z, 8Z, 11Z, 14Z, 17Z)-Eicosapentaenoic acid

7.45

307

1.92

C20H34O2

↑**

Biosynthesis of unsaturated fatty acids

11-Deoxycorticosterone

6.08

331

2.80

C21H30O3

↑**

Steroid hormone biosynthesis

Retinol

7.95

287

1.56

C20H30O

↑**

Retinol metabolism

  1. ↑: upregulated, ↓: downregulated; *P < 0.05, **P < 0.01.