Table 1 Demographical, clinical and neuropsychological data of sample group.

From: Aging, sex and cognitive Theory of Mind: a transcranial direct current stimulation study

 

Anodal vs. sham tDCS (n = 30)

Cathodal vs. sham tDCS (n = 30)

p-value*

Cut-off

Male (n = 15)

Female (n = 15)

Male (n = 15)

Female (n = 15)

Age (years)

68.3 (5)

67.5 (7)

67.1 (4)

68.1 (5)

0.895

 

Education (years)

10.4 (5)

11.6 (4)

11.1 (4)

11.4 (4)

0.882

 

Interpersonal Reactivity Index (IRI), total score

88.5 (8)

90.0 (8)

87.1 (9)

91.9 (10)

0.569

 

Reading the Mind in the Eyes Test (RMET)

21.1 (4)

23.1 (3)

20.7 (5)

21.4 (4)

0.534

 

Mood and Anxiety Assessment

Geriatric Depression Scale (GDS)

2.4 (2)

4.8 (5)

2.5 (2)

5.1 (4)

0.120

<11

State-Trait Anxiety Inventory (STAI)-State

30.4 (7)

31.9 (7)

30.1 (6)

31.3 (6)

0.600

 

State-Trait Anxiety Inventory (STAI)-Trait

33.9 (7)

36.2 (9)

32.7 (6)

38.9 (10)

0.350

 

Subjective Memory Complaints

Everyday Memory Questionnaire (EMQ)

46.1 (15)

45.5 (15)

46.9 (11)

44.9 (11)

0.918

 

Cognitive Reserve

Cognitive Reserve Index (CRI), total score

111.3 (15)

116.4 (16)

110.5 (16)

117.1 (15)

0.553

 

Cognitive Assessment

Screening for dementia

MMSE

28.9 (1)

28.9 (1)

28.5 (1)

29.1 (1)

0.618

≥24

Non-Verbal Reasoning

Raven’s colored progressive matrices

30.8 (3)

29.7 (5)

30.4 (3)

30.9 (4)

0.896

>17.5

Memory

Digit Span (forward)

5.6 (1)

6.0 (1)

5.3 (1)

5.9 (1)

0.489

>4.25

Story Recall

12.5 (3)

14.0 (4)

12.0 (4)

14.0 (3)

0.432

>7.5

RAVLT (Immediate recall)

44.0 (8)

47.6 (7)

44.3 (10)

53.2 (9)

0.020

>28.52

RAVLT (Delayed recall)

8.5 (2)

10.2 (3)

8.9 (2)

11.6 (3)

0.028

>4.68

Rey-Osterrieth Complex Figure (ROCF), recall

17.8 (6)

16.6 (6)

18.1 (6)

18.3 (3)

0.766

>9.46

Language

Token Test

33.7 (2)

34.0 (1)

33.4 (2)

34.3 (1)

0.280

>26.25

Verbal Fluency, phonemic

36.0 (9)

39.1 (14)

35.4 (10)

42.4 (9)

0.291

>16

Verbal Fluency, semantic

49.1 (9)

48.9 (12)

50.1 (7)

48.1 (8)

0.959

>24

Naming Objects (B.A.D.A)

28.9 (1)

27.9 (2)

28.8 (1)

28.6 (1)

0.733

 

Naming Actions (B.A.D.A)

26.5 (1)

25.5 (3)

25.9 (1)

26.4 (2)

0.471

 

Wechsler Adult Intelligence Scale – Vocabulary

38.6 (13)

44.0 (7)

36.7 (13)

41.5 (8)

0.412

 

Praxis

Rey-Osterrieth Complex Figure (ROCF), copy

31.6 (3)

30.9 (4)

31.5 (2)

30.9 (3)

0.896

>28.87

Attentional and Executive Functions

Trial Making Test-A (sec)

35.9 (7)

41.5 (15)

36.0 (8)

40.9 (15)

0.769

<94

Trial Making Test-B (sec)

137.2 (67)

118.8 (60)

149.1 (77)

114.7 (44)

0.204

<283

Stroop test – interference effect on time (sec)

24.5 (12)

23.9 (8)

25.5 (13)

24.0 (9)

0.904

<36.92

Stroop test – interference effect on errors

0.6 (1)

0.8 (1)

0.6 (1)

0.7 (1)

0.919

<4.24

Digit Span (backward)

4.6 (1)

4.7 (1)

4.3 (1)

4.5 (1)

0.558

>2.64

Wisconsin Card Sorting Test (WSCT) – Global score

66.5 (35)

58.5 (43)

77.5 (34)

48.5 (36)

0.250

<90.6

WSCT – Perseverative responses

21.4 (15)

22.2 (17)

26.3 (17)

19.8 (19)

0.647

<42.7

WSCT – Non Perseverative errors

20.9 (12)

17.1 (13)

24.1 (12)

14.1 (11)

0.095

<30.0

WSCT – Failure to maintain the set

1.5 (1)

1.0 (1)

1.5 (1)

0.9 (1)

0.207

<4

Flanker Task–Effect of Incongruency on RTs (ms)

174.4 (74)

134.1 (99)

174.2 (71)

137.4 (38)

0.366

 

Flanker Task–Effect of Congruency on RTs (ms)

2.2 (54)

0.5 (45)

0.6 (56)

4.3 (42)

0.968

 
  1. Raw scores are reported (SD between parentheses). MMSE: Mini Mental State Examination, RAVLT: Rey Auditory Verbal Learning Test, B.A.D.A (Batteria per l’Analisi dei Deficit Afasici), sec: seconds, RTs: Reaction Times, ms: milliseconds.*p-value related to the Freedman Analysis comparing four experimental Groups (anodal vs. sham female participants group, anodal vs. sham male participants group, cathodal vs. sham female participants group and cathodal vs. sham male participants group). Values in bold indicate significant difference (p < 0.05). Cut-off scores according to Italian normative data are reported.