Table 4 Results of univariate and multivariate regression analyses for factors independently contributing to BOT-Tissue.

From: Influence of age and gender on the pulse waveform in optic nerve head circulation in healthy men and women

Regression analysis

Univariate

Multivariate

Explanatory variables

β

95% CI

β

95% CI

Men = 1, Women = 0

0.15

0.87–2.19

0.10\(\frac{\ast }{\ast }\)

0.31–1.65

Age

−0.51

−0.21 to −0.21

−0.39

−0.21 to −0.26

Height

0.23

0.09–0.16

0.06

−0.004 to 0.07

Weight

0.13

0.02–0.07

0.04

−0.01 to 0.13

BMI

0.02

−0.06 to 0.10

  

Heart rate

0.46

0.17–0.22

0.48

0.18–0.22

MABP

−0.21

−0.08 to −0.04

−0.23

−0.09 to −0.05

Pulse pressure

−0.33

−0.15 to −0.10

−0.08\(\frac{\ast }{\ast }\)

−0.05 to −0.01

Spherical refraction

−0.23

−0.49 to −0.28

−0.08*

−0.21 to −0.05

IOP

 

−0.03

−0.15 to 0.06

 

OPP

−0.20

−0.12 to −0.06

White blood cells

0.07*

0.01–0.36

−0.03

−0.22 to 0.05

Red blood cells

0.21

1.37–2.54

0.04

−0.15 to 0.89

Platelets

0.08*

0.001–0.01

−0.04

−0.01 to 0.001

Hematocrit

0.19

0.15–0.29

eGFR

0.07*

0.001–0.04

−0.06*

−0.03 to −0.004

Current smoking

0.12

0.48–1.70

0.005

−0.42 to 0.51

(+ = 1, − = 0)

  1. Objective variable = BOT-Tissue. Multivariate regression analysis: R2 = 0.54, p < 0.0001.
  2. *p < 0.05, \(\frac{\ast }{\ast }{\rm{p}} < 0.001\), p < 0.0001.