Figure 2 | Scientific Reports

Figure 2

From: Dengue infection in mice inoculated by the intracerebral route: neuropathological effects and identification of target cells for virus replication

Figure 2

Morbidity and mortality of BALB/c mice inoculated with NGC DENV2. BALB/c mice were inoculated with the neuroadapted DENV2 by the i.c. route. Mock control group were injected with noninfected culture cell supernatant. Mortality and clinical signs of infection were monitored during 13 dpi. Morbidity score and mortality were noted according to an arbitrary scale ranging from 0 to 4 (0 = absence of morbidity, 1 = mild paralyses in one hind leg or alteration of the spinal column with small bump, 2 = one severe hind leg paralyses and alteration of the spinal column with small bump or two severe hind leg paralyses, 3 = two severe hind leg paralyses and bump deformed spinal column and 4 = death). Red line indicates the median of mouse morbidity in each timepoint of infection.

Back to article page