Figure 5
From: Landscape of heart proteome changes in a diet-induced obesity model
Overview of the obesity effects over cardiomyocyte proteome. The identified proteins are shown according to the magnitude of fold-change; red color for proteins up-regulated and blue color for proteins down-regulated in the myocardium of Western diet-induced obese rats compared to their controls. ROS, reactive oxygen species; AGEs, advanced glycation end products; Val, Ile, and Leu, valine, isoleucine, and leucine; BCAA, branched-chain amino acids; P5C, pyrroline-5-carboxylate; OAA, oxaloacetate; α-KG, α-ketoglutarate; TCA, tricarboxylic acid cycle; SSA, succinate semialdehyde; I, II, III, IV, and V, complexes of mitochondrial oxidative phosphorylation (I-IV: respiratory chain complexes; V: ATP synthase complex); CK, creatine kinase; Cr, creatine; PCr, phosphocreatine; SR, sarcoplasmic reticulum. The detailed description of protein names is shown in Supplementary Tables S3 and S4.
