Figure 6
From: Landscape of heart proteome changes in a diet-induced obesity model
Pathways validation of proteomic data. The protein expression levels of (A) platelet glycoprotein 4 (CD36) and (B) fatty acid-binding protein (FABP3) were measured by Western blot and normalized to beta-actin (internal control) in myocardium from control and Western diet (WD) groups (n = 4–6/group). A representative Western blot and quantification of protein levels are shown. Images of blots have been cropped; the full-length blots are presented in Supplementary Fig. S2. Cardiac levels of (C) malondialdehyde (MDA) and (D) carbonylated protein of control and WD groups (n = 8–13/group). Values are mean ± SD or median (Min-Max). Student’s t‐test (in A, B, and D) or Mann-Whitney U-test (in C) for independent samples.
