Table 1 Clinical characteristics of the participants.

From: Unpacking the aggregation-oligomerization-fibrillization process of naturally-occurring hIAPP amyloid oligomers isolated directly from sera of children with obesity or diabetes mellitus

 

Control (n = 5)

Obesity (n = 5)

T2DM (n = 5)

T1DM (n = 5)

P

Sex [fem], n (%)

2 (40%)

2 (40%)

3 (60%)

2 (40%)

0.895

Age [months]

166 (133, 183)

159 (124, 188)

174 (129, 202)

158 (133, 210)

0.915

ZS IMC (DE)

0.21 (−0.05, 0.53)

2.86 (2.63, 3.96)

0.71 (−0.34, 2.55)

−0.46 (−1.07, 1.17)

<0.001

Evolution [months]

28 (12, 56)

30 (0, 60)

0.882

Glucose [mg/dL]

91 (81, 92)

95 (90, 98)

103 (96, 308)

300 (185, 518)

0.013

HbA1c [%]

5.6 (5.2, 6.0)

4.9 (4.6, 5.1)

7.7 (5.3, 12.8)

12.5 (10.8, 14.0)

0.002

Toral cholesterol [mg/dL]

92 (74, 140)

151 (105, 184)

169 (100, 312)

178 (123, 212)

0.044

HDL-C [mg/dL]

43 (33, 57)

33 (31, 40)

50 (32, 68)

41 (38, 48)

0.072

Triglycerides (mg/dL)

65 (52, 115)

195 (120, 259)

173 (50, 537)

82 (48, 400)

0.066

Uric acid (mg/dL)

6.4 (3.9, 6.7)

5.5 (3.5, 6.7)

4.3 (3.6, 4.9)

3.6 (3.1, 9.3)

0.463

Insulin Tx. [Sí], n (%)

0 (0%)

6 (100%)

0.002

Insulin dosage

0.81 (0.54, 1.14)

  1. T2DM: type 2 diabetes mellitus group, T1DM: type 1 diabetes mellitus group, n: sample size. P values were calculated by chi-square teste, if the dependent variable was categorical, and by Welch’s test, if the dependent variable was continuous. The pairs do not share the same letter were different al the level of p < 0.05.