Figure 3
From: Fluorescence imaging reversion using spatially variant deconvolution

SAIRC improvement in the quality of fluorescence images of a mouse containing a 4T1 tumor injected with Integrisense 750. (a) Upper: color image of the back of a mouse bearing a 4T1 tumor after embedding in OCT compound. Lower: the corresponding raw fluorescence image of the tissue block. Scalebar: 1 mm. (b) Upper: color image of a thin slice (50 μm) from the OCT-embedded tissue block in front of a black background. Lower: the corresponding fluorescence image of the thin slice, which served as the ground truth image. (c) Upper: sigma map acquired from the scanning process (color bar in mm). Lower: corrected fluorescence image after the implementation of SAIRC. (i–iii): Zoomed-in areas of the regions of interest in the lower images in panels (a–c).