Figure 1

Clinical strains from persistent infections bind laminin. Twenty-five clinical Pseudomonas aeruginosa strains were examined in a direct binding assay (DBA) comprising [125I]-laminin 111. Radioactivity was recorded in a liquid scintillation counter after unbound laminin was removed by thorough washing. The violin graphs show median and quartiles, and each isolate from the lung of patients with cystic fibrosis (CF, squares), patients with urinary tract infections (triangles), bacteremia (down-facing triangle) and persistent wound infections (diamonds) as indicated. cpm; counts per minute. *p ≤ 0.05; **p ≤ 0.01; ***p ≤ 0.001. Statistical significances were calculated using one-way ANOVA with Tukey’s multiple comparison test.