Figure 4
From: Transcriptomic responses in mouse blood during the first week after in vivo gamma irradiation
Gene expression profile clusters. The maSigPro R package was used to identify genes with significant changes in expression over time, and with significant differences in response as a function of dose. The gene expression profiles were grouped into four clusters that showed distinct temporal profiles, and the median expression of all genes in the cluster was plotted for each dose and time. Solid lines connect the average expression to show the trends for each dose group, and the dashed lines show the regression curves fitted to the data. Gene lists and ontology analysis for each cluster are available in Supplementary File 3.
