Figure 4
From: Structural consequences of BMPR2 kinase domain mutations causing pulmonary arterial hypertension
Locations of PAH-associated missense mutations in the BMPR2 structure. Ribbon representation is shown for the kinase N and C-lobes and coloured green and brown, respectively. The positions of mutations are indicated by blue stick and space-fill representations of the wild-type side chains. The distribution of PAH-associated mutations in BMPR2 is widespread in the kinase C-lobe, but more limited in the N-lobe.
