Figure 4
From: Comparative analysis of corrected tiger genome provides clues to its neuronal evolution

The adaptive divergence of Notch signalling pathway in tiger. (a) The regression of XD-score and Fisher’s q-value of KEGG pathways. (b) Network diagram of genes showing the interaction of MSA genes with the rest of the genes of the Notch signalling pathway. The nodes represent individual genes of the NOTCH pathway in which MSA genes are shown in red and other genes of the pathway are shown in green. The edges in the network represent the protein-protein interactions among the genes obtained from STRING database. (c) Schematic representation of the Notch signalling pathway from KEGG with the genes showing multiple signatures of adaptation highlighted in Red. The pathway diagram was constructed using KEGGscape plug-in72 in Cytoscape.