Table 1 Z-average diameters, polydispersity indexes (PDI), zeta potentials and loading % (w/w) of MeJA-loaded PLGA NPs synthesized with the microfluidic device working at different MeJA concentrations with a bioactive/polymer ratio of 1/10 (w/w).
MeJA* (mg/mL) | PLGA** (mg/mL) | NPs Diameter (nm) | PDI | Zeta potential (mV) | Loading % (w/w) |
|---|---|---|---|---|---|
0.01 | 0.1 | 43 ± 21 | 0.254 | −26 ± 11 | 4.6 |
0.05 | 0.5 | 52 ± 17 | 0.127 | −31 ± 7 | 5.2 |
0.10 | 1 | 68 ± 22 | 0.112 | −22 ± 8 | 5.4 |
0.20 | 2 | 73 ± 13 | 0.066 | −34 ± 6 | 5.9 |
0.35 | 3.5 | 105 ± 36 | 0.132 | −17 ± 9 | 5.2 |
0.50 | 5 | 124 ± 33 | 0.098 | −27 ± 4 | 4.9 |