Figure 1

Gender and frailty interaction directly adjusted survival curves. Each directly adjusted curve, estimated at a specific factor and interaction value, is compared to the overall observed survival Kaplan Meier curve (red continuous line) and exemplifies the survival that would be observed if all patients in the study population had had the given specific factor and interaction value. Continuous black line = no frail female. Dashed black line = frail female. Continuous blue line = no frail male. Dashed blue line = frail male. The male lines fully overlap.