Figure 6 | Scientific Reports

Figure 6

From: A multi-genotype therapeutic human papillomavirus vaccine elicits potent T cell responses to conserved regions of early proteins

Figure 6

Detection of circulating 5GHPV3-specific T cells by IFN-γ Elispot assays performed in women with prevalent or prior hrHPV infection. PBMCs were collected from healthy asymptomatic women aged 16–24 years; Cohort 1 (left) and women aged 25–55 years referred to colposcopy for investigation of abnormal cervical cytology; Cohort 2 (right). Dotted line at 25 SFU/million PBMCs shows negative cut-off (calculated as mean of negative wells plus 3 SD). Study participants shown in the graphs are those that had a detectable response (>25 SFU/million PBMCs) to either of the reference peptide sets.

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