Table 1 Hormone receptor (ER and PgR) and HER2 status of the primary BCR and their matched BCBM cases.

From: A novel panel of differentially-expressed microRNAs in breast cancer brain metastasis may predict patient survival

Patient No

Status

ER status of the 1oBC

ER status of BM

PgR status of the 1oBC

PgR status of BM

HER2 status of the 1oBC

HER2 status of BM

Time (months) between breast-brain surgeries/recurrence

Time (months) between breast surgery and death

119

ER+

+

+

+

62

85

560

ER+/PgR+

+

+

+

+

97

103

666

ER+/PgR+

+

+

38

55

690

ER+/PgR+

+

+

+

+

44

72

707

HER2+/ER+

+

+

+

48

89

712

ER+

+

28

32

725

ER+/PgR+

+

+

+

22

26

756

HER2+/ER+

+

+

+*

25

53

827

TN

+

16

NA

912

ER+/PgR+

+

+

+

+

60

94

943

TN

36

61

972

HER2+/HR+

+

+

+

+

+

27

29

1004

ER+

+

+

10

NA

1020

TN

+

26

NA

1148

ER+/PgR+

+

+

+

+

51

52

1386

ER+

+

11

NA

1662

ER+

+

+

39

54

1709

TN

+

23

25

12051

ER+

+

6

29

12321

ER+

+

14

64

12372

HER2+

NA

NA

+

NA

14

25

12364

HER2+

+

+

29

64

13147

ER+/PgR+

+

+

24

42

13263

ER+

+

+

30

42

13630

TN

30

31

13631

HER2+

NA

+

+*

21

30

13692

TN

NA

35

44

14063

TN

NA

26

31

14222

ER+/PgR+

+

+

+

+

Synchronous

50

15311

ER+/PgR+

+

+

+

+

NA

174

RCSI_1

HER2+

+

+

20

31

RCSI_2

HER2+/ER+

+

+

+

+

37

104

RCSI_3

HER2+

+

+

67

115

RCSI_5

ER+

+

+

+

53

74

RCSI_6

TN

23

40

RCSI_7

ER+

+

+

+

53

73

RCSI_8

ER+

+

+

59

97

RCSI_9

HER2+

+

+

17

40

RCSI_10

HER2+

+

+

70

112

RCSI_11

ER+

+

8

17

  1. The table indicates the differences of the ER, PgR and HER2 status between the primary BCR and BCBM cases. Samples were collected from Walton Tissue Bank, Liverpool, UK and Royal College of Surgeons Ireland (RCSI) National Breast Cancer Bioresource, Ireland.
  2. NA: Not available,+: positive, −: negative.
  3. *2+, FISH not available.