Figure 2

Nociceptive behaviors after formalin/saline injection during and without the temporal bisection task. Rats received single injections of 1% formalin solution (50 μl) into the hind paw. Nociceptive behavior was measured as the time spent in lifting and licking the injected paw, which varied as a function of time. Formalin injection induced more nociceptive behaviors during 70 min without the task (a) and during the task (b). Cumulative paw-licking scores in phases 1 (middle panel of a, b) and 2 (left panel of a, b) after formalin injection were significantly higher than these after saline injection. *p < 0.05, **p < 0.01, ***p < 0.001 vs. saline injection; n = 10. Results are shown as means ± SEM.