Figure 5 | Scientific Reports

Figure 5

From: Synthesis and preclinical validation of novel P2Y1 receptor ligands as a potent anti-prostate cancer agent

Figure 5

Induction of apoptosis by compound 1 and 2 on PCa cells. (A) Representative images of PC-3 cells stained with Annexin-V/PI in untreated, compound 1, 2, and Na3VO4 treated condition. (B) percentage of apoptotic and necrotic cell death in the corresponding condition as in A. (C) The representative images of DU-145 cells stained with Annexin-V/PI (D) the percentage of apoptosis and necrosis in DU-145 cells. Results are represented as mean of three independent experiments, mean ± S.D. *P < 0.05, versus control, n = 3.

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